The present invention relates to the treatment or prevention of skeletal disorders, at particular skeletal diseases, developed by patients that display abnormal increased activation of the fibroblast growth factor receptor 3 (FGFR3), in particular by expression of a constitutively activated mutant of FGFR3.

A curable resin composition contains a curable resin that comprises at least one non-aromatic epoxy compound, at least one non-aromatic oxetane compound, or a mixture thereof, one or more curing agents selected from Lewis acid:Lewis base complexes, and a cure accelerating amount of one or more anhydride compounds. A method accelerating the cure of a curable resin composition, comprising adding a cure accelerating amount of one or more anhydride compounds to a curable resin composition comprising a curable resin that comprises at least one non-aromatic epoxy compound or non-aromatic oxetane compound and a curing agent that comprises one or more Lewis acid-base complexes. The composition and method are useful in making fiber reinforced resin matrix composite articles.

A resin composition includes an unsaturated C═C double bond-containing polyphenylene ether resin, a polyolefin and silica; in an X-ray diffraction analysis pattern of the silica as measured by reference to JY/T 009-1996, only one diffraction peak exists in a 2θ ranging from 10° to 30°, and the diffraction peak has a full width at half maximum of 5.0° to 7.7°. The resin composition may be used to make various articles, such as a prepreg, a resin film, a laminate or a printed circuit board, and achieves improvements in at least one of the properties including dissipation factor, resin filling property in open area, hole drilling limit value, and precision of hole position Cpk.

The present invention relates to a self-adhesive article comprising a non-random fabric of bundles of carbon fibres and a thermosetting epoxy resin composition. The self-adhesive article exhibits high surface adhesion and excellent dimensional stability at room temperature. The self-adhesive article is ideally suited to reinforce structural components, particularly vehicles or ancillary vehicle components. The structural components reinforced by the self-adhesive article exhibit improved impact and torsional strength.

A heat-sealable composite film comprising an oriented polyester substrate layer having a first and second surface is provided. Disposed on the first surface of the substrate layer is a heat- sealable polymeric coating layer comprising a styrenic linear block copolymer thermoplastic elastomer, an ethylene vinyl acetate (EVA) copolymer and a tackifying resin. Also described is a sealed container comprising a receptacle containing a food product, and a lid formed from said heat-sealable composite film.

A substrate for use in an electronic skin is disclosed herein. The substrate comprises a base polymer layer, and a first intermediate polymer layer attached to the base polymer layer by a first adhesive layer. The first intermediate polymer layer comprises a first intermediate polymer in which electron-rich groups are linked directly to one another or by optionally substituted C.sub.1-4 alkanediyl groups. A first conductive layer is attached to the first intermediate polymer layer by a second adhesive layer or by multiple second adhesive layers between which a second intermediate polymer layer or a second conductive layer is disposed.

A polystyrene (PS) composition for making an extruded foam, the PS composition comprising polystyrene, a blowing agent, and an additive selected from glycerol monostearate (GMS), glycerol tri-stearate (GTS), mineral oil (MO), epoxidized soy oil (ESO), epoxidized polybutadiene, or combinations thereof. Methods of producing a low density polystyrene (PS) foam are also provided.

Disclosed herein are modified diene-containing (co)polymers, in particular, modified styrene-butadiene copolymer, which can be used as flame retardants for expandable polystyrene polymer compositions. In particular, disclosed is a modified diene-containing (co)polymer, a method for preparing it, and use as a flame retardant for expandable polystyrene. The modified diene-containing (co)polymer claimed in the invention is characterized by high thermostability, namely, a 5% weight loss temperature of at least 180° C., a molecular weight of at least 1500 g/mol and a halogen content of at least 35 wt. %; the content of tertiary and/or allyl halogenides is in the range from 0 to less than 1.5 wt. %, and also does not affect the polymerization process and the formation of polystyrene granules either, and allows to obtain polystyrene granules with a yellowness index of 2 to 6 units, comparable to the yellowness index of polystyrene granules containing HBCD (from 0 to 3 units).

A method for evaluating the compatibility of a thermosetting resin composition containing at least two kinds of resins and an inorganic filler, the method including the following steps 1A and 2A: Step 1A: a step of obtaining a reflected electronic image of the cross section of a cured product of the thermosetting resin composition using a scanning electron microscope at an observation magnification of 50 to 250 times; and Step 2A: a step in which, in the reflected electronic image, a phase-separated resin region is referred to as a separation part and the remaining region is referred to as a non-separation part, and the image is binarized such that the separation part has one value and the non-separation part has the other value, and the area ratio of the region of the non-separation part of the resultant binarized image to the total region of the binarized image (area of the region of the non-separation part×100/area of the total region of the binarized image) is calculated as the area ratio Rw of the non-separation part.

The present disclosure is directed to rubber compositions comprising at least one rubber, at least one reinforcing carbon black filler, and a whey protein component. The whey protein component is in an amount sufficient to provide about 0.1 to about 10 phr whey protein. The present disclosure is also directed to methods of preparing such rubber compositions and to tire components containing the rubber compositions disclosed herein.