The present invention relates to stabilization of RNA, in particular mRNA, and an increase in mRNA translation. The present invention particularly relates to a modification of RNA, in particular in vitro-transcribed RNA, resulting in increased transcript stability and/or translation efficiency. According to the invention, it was demonstrated that certain sequences in the 3′-untranslated region (UTR) of an RNA molecule improve stability and translation efficiency.

The present invention relates to stabilization of RNA, in particular mRNA, and an increase in mRNA translation. The present invention particularly relates to a modification of RNA, in particular in vitro-transcribed RNA, resulting in increased transcript stability and/or translation efficiency. According to the invention, it was demonstrated that certain sequences in the 3′-untranslated region (UTR) of an RNA molecule improve stability and translation efficiency.

Organizational systems and associated components and methods for garages, sheds, basements or other spaces that have exposed wall or ceiling elongated members are provided. One such component includes a bracket having a first wall, a second wall facing the first wall and spaced apart from the first wall, and a third wall interconnecting the first and second walls. The first, second and third walls cooperatively define a channel for receiving the elongated member. The bracket includes an interface for releasable attachment of a storage component to the bracket. A clamp foot is movably coupled to the first wall. The clamp foot is translatable between an engaged position and a released position to respectively engage and release the elongated member received in the channel.

Organizational systems and associated components and methods for garages, sheds, basements or other spaces that have exposed wall or ceiling elongated members are provided. One such component includes a bracket having a first wall, a second wall facing the first wall and spaced apart from the first wall, and a third wall interconnecting the first and second walls. The first, second and third walls cooperatively define a channel for receiving the elongated member. The bracket includes an interface for releasable attachment of a storage component to the bracket. A clamp foot is movably coupled to the first wall. The clamp foot is translatable between an engaged position and a released position to respectively engage and release the elongated member received in the channel.

A bracket for a floating shelf comprises a solid plate with a planar back side to abut to a wall. A plurality of circular apertures extends through the solid plate and have internal screw threads. A plurality of rods is secured to the solid plate and extending therefrom, with each rod having a proximal end received within a different one of the plurality of circular apertures. The plurality of rods has external screw threads on the proximal end mating with a respective internal screw thread of respective circular apertures. The proximal ends of the plurality of rods are flush with the planar back side of the solid plate and the wail.

A multi-level cabinet storage system includes a multi-level storage container that includes a number of shelves, each with horizontal planar surfaces, coupled between the vertical opposing members. The horizontal planar surfaces of respective shelves may be aligned vertically in parallel planes. The vertical opposing members may include a rear vertical member and a front vertical member. The multi-level cabinet storage system also includes a first slide member coupled with a base of the multi-level storage container and a second slide member coupled at a first end with the rear vertical member and extending parallel with, and along, a horizontal planar surface of an upper shelf included among the shelves. The multi-level cabinet storage system also includes an external frame formed as a contiguous rigid structure coupled with the first slide member and the second slide member.

A multi-level cabinet storage system includes a multi-level storage container that includes a number of shelves, each with horizontal planar surfaces, coupled between the vertical opposing members. The horizontal planar surfaces of respective shelves may be aligned vertically in parallel planes. The vertical opposing members may include a rear vertical member and a front vertical member. The multi-level cabinet storage system also includes a first slide member coupled with a base of the multi-level storage container and a second slide member coupled at a first end with the rear vertical member and extending parallel with, and along, a horizontal planar surface of an upper shelf included among the shelves. The multi-level cabinet storage system also includes an external frame formed as a contiguous rigid structure coupled with the first slide member and the second slide member.

Various embodiments of the coupling platforms described herein are usable to couple storage units, such as modular storage units, to structures, such as to the undersides of benches or tables. One or more of the coupling platforms described herein facilitate the user supporting a newly-disengaged support unit. For example, one or more of the coupling platforms permit the user to place their hands on both sides of the storage unit to complete a disengagement between the coupling platform and the storage unit.

Various embodiments of the coupling platforms described herein are usable to couple storage units, such as modular storage units, to structures, such as to the undersides of benches or tables. One or more of the coupling platforms described herein facilitate the user supporting a newly-disengaged support unit. For example, one or more of the coupling platforms permit the user to place their hands on both sides of the storage unit to complete a disengagement between the coupling platform and the storage unit.

A wall hanging system by which a wall décor item such as a ledge, a frame, a mantel, or the like may be mounted to and hung from a wall. The wall hanging system may include the wall décor item having a rear surface and first and second mounting channels in the rear surface. The wall hanging system may also include first and second mounting brackets that are configured to be mounted to the wall. At least one of the first and second mounting brackets may have an elongated aperture through which a fastener extends for mounting that mounting bracket to the wall. As such, the mounting bracket with the elongated aperture is able to slide side-to-side along the wall while being mounted to the wall in order to properly align the first and second mounting brackets with the first and second mounting channels of the wall décor item.