Patent classifications
A61B5/407
MAGNETISM MEASURING APPARATUS
A magnetism measuring apparatus includes: a sensor array configured to detect magnetic fields generated by a living body; a current source reconfiguration unit configured to reconstruct a current source of a current flowing inside of the living body based on a magnetic field signal obtained from the sensor array. The sensor array includes first sensors configured to detect magnetic field components of many directions and second sensors configured to detect magnetic field components of directions fewer than those of the first sensors.
NEUROSTIMULATOR
- Joel W. Burdick ,
- Yu-Chong Tai ,
- John F. Naber ,
- Robert S. Keynton ,
- Victor Reggie Edgerton ,
- Roland R. Roy ,
- Yury Gerasimenko ,
- Susan J. Harkema ,
- Jonathan Hodes ,
- Claudia A. Angeli ,
- Mandheerej S. Nandra ,
- Thomas Anthony Desautels ,
- Steven L. Upchurch ,
- Douglas J. Jackson ,
- Nicholas A. Terrafranca, Jr. ,
- Yangsheng Chen
Neurostimulator devices are described. An example neurostimulator device includes a stimulation assembly connectable to a plurality of electrodes, wherein the plurality of electrodes are configured to stimulate a spinal cord. The neurostimulator device also includes an interface and at least one processor configured to modify at least one complex stimulation pattern deliverable by the plurality of electrodes by integrating data from the interface and performing a machine learning algorithm on the at least one complex stimulation pattern.
METHODS FOR DETECTING NEURONAL OSCILLATION IN THE SPINAL CORD ASSOCIATED WITH PAIN AND DISEASES OR DISORDERS OF THE NERVOUS SYSTEM
Disclosed are methods for detecting neuronal oscillation in the spinal cord of a subject. The methods can be utilized to determine that the subject has a disease or disorder of the spinal cord. The methods are useful for treating or reducing the likelihood of pain in a subject by detecting neuronal oscillation in the spinal cord and, e.g., administering a therapeutic agent to the subject. The electrode (LFP) methods disclosed herein may also be utilized to screen for a therapeutic agent that decreases neuronal oscillation in the spinal cord using a non-human animal subject.
Method and Device for Detecting a Neural Response in Neural Measurements
A method is provided for processing a neural measurement obtained in the presence of noise, in order to detect whether a locally evoked neural response is present in the neural measurement. A first neural measurement is obtained from a first sense electrode. A second neural measurement is contemporaneously obtained from a second sense electrode spaced apart from the first electrode along a neural pathway of the neural response. A neural response decay is determined, being a measure of the decay in the neural response from the first sense electrode to the second sense electrode. A ratio of the neural response decay to an amplitude normalising term is calculated. From the ratio it is determined whether a locally evoked neural response is present in the neural measurement.
Implantable Electrode Positioning
A method of surgically positioning an electrode array at a desired implantation location relative to a nerve. A temporary probe electrode is temporarily positioned adjacent to the nerve and at a location which is caudorostrally separate to the desired implantation location of the electrode array. The implanted position of the probe electrode is temporarily fixed relative to the nerve. During implantation of the electrode array, electrical stimuli are applied from one of the temporarily fixed probe electrode and the electrode array, to evoke compound action potentials on the nerve. Compound action potentials evoked by the stimuli are sensed from at least one electrode of the other of the temporarily fixed probe electrode and the electrode array. From the sensed compound action potentials a position of the electrode array relative to the nerve is determined.
THREE-DIMENSIONAL ELECTRICAL IMPEDANCE TOMOGRAPHY SYSTEM
The present disclosure provides a method for improving imaging resolution of electrical impedance tomography (EIT). More specifically, the present disclosure forms virtual electrode(s) using an electric current steering technique, which is used to improve imaging resolution of an EIT system without physically increasing a number of conducting electrodes. The EIT system of the present disclosure may includes a plurality of conducting electrodes, at least one signal generator, at least one signal receiver and at least one electric current steering device. In other words, the present disclosure applies both the electric current steering technique and the virtual electrode technique to EIT. Consequently, imaging resolution of EIT can be improved without physically increasing the number of conducting electrodes.
CHEST MEASURING DEVICE, SCOLIOSIS CORRECTION SYSTEM, SYSTEM FOR REMOTELY DIAGNOSING SPINE, AND WEARABLE MEASURING DEVICE
Provided is a chest measuring device configured to be attached to and detachable from a body and capable of inducing a correct posture of a subject and at the same time, correcting an abnormal alignment of the spine by analyzing measured values of left and right chests and generating vibrating motion to a chest that needs stimulation, a scoliosis correction system enabling a subject to conveniently measure his/her spinal condition alone without the help of others by including sensors contacting left and right ribs and left and right transverse processes of lumbar vertebrae of the subject and also including a wearable internet of things (IoT) capable of detecting sensing values of muscles used to determine a spinal condition of the subject, a system for remotely diagnosing spine remotely diagnosing the spine of a patient by processing trunk movement data of the patient collected through a wearable measuring device, and a wearable measuring device enabling a subject to self-diagnose a spinal condition and correct a posture based on the result.
CHEST MEASURING DEVICE, SCOLIOSIS CORRECTION SYSTEM, SYSTEM FOR REMOTELY DIAGNOSING SPINE, AND WEARABLE MEASURING DEVICE
Provided is a chest measuring device configured to be attached to and detachable from a body and capable of inducing a correct posture of a subject and at the same time, correcting an abnormal alignment of the spine by analyzing measured values of left and right chests and generating vibrating motion to a chest that needs stimulation, a scoliosis correction system enabling a subject to conveniently measure his/her spinal condition alone without the help of others by including sensors contacting left and right ribs and left and right transverse processes of lumbar vertebrae of the subject and also including a wearable internet of things (IoT) capable of detecting sensing values of muscles used to determine a spinal condition of the subject, a system for remotely diagnosing spine remotely diagnosing the spine of a patient by processing trunk movement data of the patient collected through a wearable measuring device, and a wearable measuring device enabling a subject to self-diagnose a spinal condition and correct a posture based on the result.
SUB-PERCEPTION CALIBRATION USING SPACE DOMAIN SCALING
An example of a system to program a neuromodulator to deliver neuromodulation to a neural target using a plurality of electrodes may comprise a programming control circuit configured to determine target energy allocations for the plurality of electrodes based on at least one target pole to provide a target sub-perception modulation field, calibrate a plurality of electrode groups in the plurality of electrodes where each of the plurality of electrode groups is in an electrode configuration and includes an electrode set of at least one electrode from the plurality of electrodes, including for each of the plurality of electrode groups receive a feedback metric to delivery of modulation energy to the neural target, and normalize the target sub-perception modulation field, including determine a space domain scaling factor using the feedback metric to account for actual electrode-tissue coupling, and apply the space domain scaling factor to the target energy allocations.
SURGICAL VISUALIZATION SYSTEMS AND RELATED METHODS
Surgical visualization systems and related methods are disclosed herein, e.g., for providing visualization during surgical procedures. Systems and methods herein can be used in a wide range of surgical procedures, including spinal surgeries such as minimally-invasive fusion or discectomy procedures. Systems and methods herein can include various features for enhancing end user experience, improving clinical outcomes, or reducing the invasiveness of a surgery. Exemplary features can include access port integration, hands-free operation, active and/or passive lens cleaning, adjustable camera depth, and many others.