Microsurgical instruments having combined illumination, laser ablation, and viscoelastic injection functions. A surgical instrument includes a probe having a main lumen and a port at a distal end thereof. The probe may further include one or more optical fibers within the main lumen, the optical fibers configured to project laser light and illumination light. Laser light may be emitted from the distal end of the probe for disrupting an ocular tissue, while illumination light may be simultaneously emitted, axially or laterally, to provide enhanced visualization of the intraocular space during tissue disruptance. Upon disrupting the tissue, a viscoelastic fluid may be injected from the port to maintain an integrity of the intraocular space.

Disclosed herein are methods, devices, and systems for treating lens protein aggregation diseases. A system is disclosed that includes a source of light energy that emits one or more beams of light energy, a focuser for focusing the one or more beams into a predetermined area of the lens epithelium, and an adjuster for adjusting at least one parameter of the one or beams. A method is also disclosed that includes focusing one or more beams of light energy from a source of light energy on to a predetermined area of an eye lens, pulsing the one or more beams, scanning the one or more beams, measuring one or more types of radiation from the predetermined area, and utilizing the one or more measured types of radiation to decide whether to stop or adjust the one or more beams.

A test device to calibrate the pulse energy of a laser device which provides pulsed laser radiation includes a measuring head with multiple measuring probes. The test device is used in such a way that by means of the laser radiation, multiple test ablations are made on a test surface, in an arrangement corresponding to the relative spatial arrangement of the measuring probes, and the depths of the test ablations are then measured, with simultaneous use of the multiple measuring probes of the measuring head.

A system and a method may be provided relating to the iris of an eye based on three-dimensional image data acquired by an optical coherence tomography.

Some embodiments of the present disclosure relate to a method and system where a fiber optic probe is obtained. In some embodiments, the fiber optic probe comprises a distal end. In some embodiments, the fiber optic probe is introduced between an outer surface of an eye and an anterior chamber of an eye. In some embodiments, the fiber optic probe is advanced into one or more portions of the eye. In some embodiments, a plurality of pulses of laser radiation are delivered through a laser and into the eye. In some embodiments, the laser is disposed at a distal end of the fiber optic probe. In some embodiments, ocular tissue of the eye is ablated with the plurality of pulses of laser radiation. In some embodiments, the ablating generates a drainage channel that extends from the anterior chamber of the eye to the subconjunctival space of the eye.

A planning system for generating control data for a treatment apparatus which creates at least one cut surface in the cornea using a laser device, and a treatment apparatus which comprises a planning system of the aforementioned type. The invention also relates to a method of generating control data for a treatment apparatus which creates at least one cut surface in the cornea using a laser device, and to a corresponding method of eye surgery. The planning system comprises a calculation means for defining the cut surfaces of the cornea, wherein the calculation means determines the cornea cuts so that the cut surfaces isolate a lenticule, which is treated according to the planned refraction correction after removal from the cornea, so that the planned refraction correction occurs after the insertion into the cornea of the recipient.

A method and apparatus for making improved surgical incisions in corrective eye surgery are provided. It was observed that a uniform elongated AK (or LRI) incision provides a non-uniform corrective effect due to non-uniform post-surgical relaxation of ophthalmic tissue. The method and apparatus leverage this observation to provide for creation of a surgical incision that is structured to be non-uniform along its length in such a manner as to at least partially counteract an expected variation in ophthalmic tissue relaxation to provide overall increased uniformity of corrective effect. An automated laser surgery system includes a laser control system configured to control laser delivery to cause selective ablation of ophthalmic tissue to provide an elongated structured incision that varies along its length in at least one of a depth, a profile, a width, and an angle of attack relative to a surface of the ophthalmic tissue.

An ophthalmological device (1) for treating eye tissue by means of pulsed laser beams (L) comprises a laser system (12) which is designed, in a first mode of operation, to generate pulsed laser beams (L) with a wavelength in the NIR infrared range and, in a second mode of operation, to generate pulsed laser beams (L) with a wavelength in the UVA ultraviolet range. The ophthalmological device (1) moreover comprises a focusing system (10) with a projection optical unit (11), which is designed, in the first mode of operation, to project the pulsed laser beams (L) in the NIR infrared range into the lens (21) of the eye, which pulsed laser beams are focused to a first spot size (d1) by means of a first zoom function (101) for the purpose of disintegrating eye tissue, and, in the second mode of operation, to project the pulsed laser beams (L) in the UVA ultraviolet range into the cornea (22) of the eye, which pulsed laser beams are focused to a second spot size (d2) which is substantially smaller than the first spot size (d1) by means of a second zoom function (102), which differs from the first zoom function (101), for the purpose of creating tissue cuts.

A method for altering an eye color of a patient with a color alteration procedure is disclosed that may include determining a laser power to deliver to stromal pigment in an iris of the eye of the patient by at least retrieving a set of laser criteria for delivery of an exposure less than 100 times a maximum permissible exposure that causes elimination of at least a portion of the stromal pigment. A laser system may be set to deliver laser light at the laser power which is less than the set of laser criteria and the laser light may be delivered with the laser system.

The invention provides an excimer laser system including a means for calibrating laser output to compensate for increased variation in laser optical fibers.