Devices to perform femtolaser ablation and phacoemulsification are physically and/or operationally combined. In some embodiments the femtolaser ablation and phacoemulsification are housed together, and in other embodiments they are housed separately, but operated through a common display screen. At least some software can be shared by the femtolaser ablation and phacoemulsification functionalities. A non-transitory computer-readable memory can provide data that can be used to operate each of at least one femtolaser ablation functionality and at least one phacoemulsification functionality.

Disclosed are systems, devices and methods for laser microporation for rejuvenation of tissue of the eye, for example, regarding aging of connective tissue and rejuvenation of connective tissue by scleral rejuvenation. The systems, devices and methods disclosed herein restore physiological functions of the eye including restoring physiological accommodation or physiological pseudo-accommodation through natural physiological and biomechanical phenomena associated with natural accommodation of the eye. In some embodiments, the laser system may be configured to treat ocular tissue off axis or in a region of the eye which is distinct from the visual axis or directed away from the pupil of the eye where the gaze of the eye is.

An ophthalmic laser surgical system has a built-in imaging sensor for measuring laser focal spot size. An objective lens focuses the laser beam to a focal spot near a reflective surface, scans the focal spot in the depth direction, and focuses light reflected by the reflective surface to form a back-reflected light. A two-dimensional imaging sensor receives a sample of the back-reflected light to generate images of the back-reflected light. During the depth scan, the image contains a well-focused light spot when the laser focal spot is located at a fixed offset distance before the reflective surface, but the light spot in the images is otherwise defocused. The images generated during the scan are analyzed to find the smallest light spot size among the images. The laser focal spot size is then calculated from the smallest light spot size using a magnification factor which is a system constant.

The present invention discloses a method and an apparatus for treating an ocular tissue. The method for treating the ocular tissue includes generating a femtosecond laser beam from a laser source; orientating the femtosecond laser beam toward the ocular tissue; and defining a target area in the ocular tissue using the femtosecond laser beam, wherein the target area contains a sharp-edge part and a to-be-removed part, in which the sharp-edge part has a minimum thickness being gradually reduced to zero and is ablated by the femtosecond laser beam while the target area is defined; and removing the to-be-removed part of the target area from the ocular tissue.

The disclosure provides a system that may: determine first multiple focal point distances associated with respective multiple positions of a plane orthogonal to a laser beam; determine second multiple focal point distances associated with the respective multiple positions via for each position of the multiple positions: determine multiple intensity values associated with respective multiple interim focal point distances, each interim focal point distance greater than each focal point distance of the first multiple focal point distances associated with the position; determine an interim focal point distance respectively associated with a maximum intensity value; and determine a focal point distance as the interim focal point distance; and determine a depth of at least one incision in an eye based at least on differences between each of the second multiple focal point distances and each respective one of the first multiple focal point distances.

An imaging probe comprises a camera or endoscope with an external detector array, in which the probe is sized and shaped for surgical placement in an eye to image the eye from an interior of the eye during treatment. The imaging probe and a treatment probe can be coupled together with a fastener or contained within a housing. The imaging probe and the treatment probe can be sized and shaped to enter the eye through an incision in the cornea and image one or more of the ciliary body band or the scleral spur. The treatment probe may comprise a treatment optical fiber or a surgical placement device to deliver an implant. A processor coupled to the detector can be configured with instructions to identify a location of one or more of the ciliary body band, the scleral spur, Schwalbe's line, or Schlemm's canal from the image.

An imaging probe comprises a camera or endoscope with an external detector array, in which the probe is sized and shaped for surgical placement in an eye to image the eye from an interior of the eye during treatment. The imaging probe and a treatment probe 500 can be coupled together with a fastener or contained within a housing. The imaging probe and the treatment probe 500 can be sized and shaped to enter the eye through an incision in the cornea and image one or more of the ciliary body band or the scleral spur. The treatment probe 500 may comprise a treatment optical fiber or a surgical placement device to deliver an implant. A processor coupled to the detector can be configured with instructions to identify a location of one or more of the ciliary body band, the scleral spur, Schwalbe's line, or Schlemm's canal from the image.

A beam deflection device for a laser device is disclosed for generating a laser pattern on or in a material by means of a laser beam) of the laser device. The beam deflection device includes at least one reflecting or dispersive beam offset element, which is formed for spatially offsetting the laser beam in relation to an optical axis of a laser generating device of the laser device. The beam deflection device further includes a rotating, dispersive optical element, which is formed for generating a rotation pattern as the laser pattern from the previously offset laser beam. Further, a laser device, a computer program as well as to a computer-readable medium are disclosed.

A device for defining a flap geometry of a flap for laser treatment of a human eye comprises a control unit programmed to evaluate ablation profile data of an ablation profile for a laser ablation treatment of a human cornea and to define the flap geometry based on this evaluation.

Systems, devices and methods are provided to deliver microporation medical treatments to improve biomechanics, wherein the system includes a laser for generating a beam of laser radiation on a treatment-axis not aligned with a patient's visual-axis, operable for use in subsurface ablative medical treatments to create an array pattern of micropores that improves biomechanics. The array pattern of micropores is at least one of a radial pattern, a spiral pattern, a phyllotactic pattern, or an asymmetric pattern.