An imaging probe comprises a camera or endoscope with an external detector array, in which the probe is sized and shaped for surgical placement in an eye to image the eye from an interior of the eye during treatment. The imaging probe and a treatment probe can be coupled together with a fastener or contained within a housing. The imaging probe and the treatment probe can be sized and shaped to enter the eye through an incision in the cornea and image one or more of the ciliary body band or the scleral spur. The treatment probe may comprise a treatment optical fiber or a surgical placement device to deliver an implant. A processor coupled to the detector can be configured with instructions to identify a location of one or more of the ciliary body band, the scleral spur, Schwalbe's line, or Schlemm's canal from the image.

An imaging probe comprises a camera or endoscope with an external detector array, in which the probe is sized and shaped for surgical placement in an eye to image the eye from an interior of the eye during treatment. The imaging probe and a treatment probe can be coupled together with a fastener or contained within a housing. The imaging probe and the treatment probe can be sized and shaped to enter the eye through an incision in the cornea and image one or more of the ciliary body band or the scleral spur. The treatment probe may comprise a treatment optical fiber or a surgical placement device to deliver an implant. A processor coupled to the detector can be configured with instructions to identify a location of one or more of the ciliary body band, the scleral spur, Schwalbe's line, or Schlemm's canal from the image.

An imaging probe comprises a camera or endoscope with an external detector array, in which the probe is sized and shaped for surgical placement in an eye to image the eye from an interior of the eye during treatment. The imaging probe and a treatment probe can be coupled together with a fastener or contained within a housing. The imaging probe and the treatment probe can be sized and shaped to enter the eye through an incision in the cornea and image one or more of the ciliary body band or the scleral spur. The treatment probe may comprise a treatment optical fiber or a surgical placement device to deliver an implant. A processor coupled to the detector can be configured with instructions to identify a location of one or more of the ciliary body band, the scleral spur, Schwalbe's line, or Schlemm's canal from the image.

An apparatus, such as lenses, a system and a method for providing custom ocular aberrations that provide higher visual acuity. The apparatus, system and method include inducing rotationally symmetric aberrations along with an add power in one eye and inducing non-rotationally symmetric aberrations along with an add power in the other eye to provide improved visual acuity at an intermediate distance.

Example eye treatments determine an area at a surface of a cornea for delivery of a cross-linking agent. The example treatments disrupt tissue at the area at the surface of the cornea up to a depth corresponding to apical layers of superficial squamous cells of the cornea, e.g., no greater than approximately 10 μm to approximately 15 μm. The example treatments apply a cross-linking agent to the area at the surface of the cornea. The cross-linking agent is transmitted through the disrupted area at a greater rate relative to non disrupted areas of the cornea. The example treatments deliver photoactivating light to the cornea. The photoactivating light activates the cross-linking agent to generate cross-linking activity in the cornea.

A drug delivery device includes a catheter; a retention cap attached to an end of the catheter, having an operably openable surface; a flexible membrane having a rim securely connected to an inner surface of the catheter to define a first volume and a second volume therein, such that the second volume is substantially the same as a desired drug volume; and a pressurizable member coupled to the catheter. In use, the desired drug volume is preloaded into the second volume of the catheter that in turn is slided into a guidance device, when the guidance device is placed in a target, the pressurizable member applies a pressure into the first volume to exert a force upon the flexible membrane to operably squeeze the second volume, which in turn pressurizes the operably openable surface of the retention cap to open, thereby unloading the desired drug volume into the target.

Systems for treatment of glaucoma comprise an excimer laser, a plurality of fiber probes, and a processor. Each fiber probe is attachable to the excimer laser to treat a subject having glaucoma by delivering shots from the laser. The processor is configured to monitor and limit a variable number of shots delivered by each fiber probe, the number of shots delivered by each fiber probe programmable within a range. Methods of treating glaucoma include programming a fiber probe to deliver a number of shots from an excimer laser. The fiber probe is inserted into an eye of a subject having glaucoma and adjusted to a position transverse to Schlemm's canal in the eye. A plurality of shots is applied from the excimer laser source while the probe is in the transverse position, thereby treating glaucoma by creating a plurality of perforations in Schlemm's canal and/or the trabecular meshwork.

A method for providing control data of an eye surgical laser of a treatment apparatus is disclosed for a treatment on a human or animal eye. The method optimizes a target conflict between low stress for a patient and efficacy of a laser. The method includes, as performed by a control device, determining a patient-specific parameter set, which relates to at least one physiological characteristic of the eye, determining at least one physical parameter for the eye surgical laser depending on the patient-specific parameter set, wherein the physical parameter relates to a physical characteristic of a laser beam of the laser, and providing control data for controlling the eye surgical laser, which includes the physical parameter.

The invention relates to a method for providing control data for an eye surgical laser of a treatment apparatus for the removal of a tissue from a human or animal cornea. The method includes ascertaining a temperature distribution, which is expected in the cornea per laser pulse, determining a laser pulse sequence of a preset laser pulse distribution for removing the tissue by means of a temperature model of the cornea, wherein a respective laser pulse position in the cornea is preset by the laser pulse distribution and wherein it is preset by the laser pulse sequence, in which order the preset laser pulse positions are irradiated with the respective laser pulses, wherein a temperature profile of the cornea is calculated by means of cumulated temperature distributions of the laser pulses in the temperature model and a difference profile to a preset limit temperature profile is determined, and wherein the order of the laser pulses is ascertained depending on the difference profile for determining the laser pulse sequence, and providing control data for controlling the eye surgical laser, which uses the laser pulse sequence for removing the tissue.

Disclosed are a method and a device for controlling an eye surgery system, wherein a light pattern is generated on an eye by an illumination device and is captured by a camera unit while the patient is in the position in which he or she will undergo the surgery. At least one property of the eye characterizing the current orientation of the eye during the surgery is determined from the light pattern by a computing unit.