Implantable drug delivery devices include a housing having a closed drug reservoir lumen bounded by a first wall structure and a hydrophilic second wall structure, and a drug contained in the drug reservoir lumen, wherein the first wall structure is impermeable to the drug and the second wall structure is permeable to the drug. Methods of providing controlled release of drug to a patient include deploying a drug delivery device in the patient releasing a drug from the drug reservoir lumen via diffusion through the second wall structure.

A ureteral stent is provided. The stent may include a first section having a first wall defining a first luminal section. The stent may further include a second section having a second wall defining a second luminal section. The second section can be enabled to substantially close at times external pressure is applied to the stent.

Devices, systems, and methods herein relate to performing dialysis to manage a chronic condition such as end-stage renal disease. These systems and methods may allow a patient to orally ingest a potable dialysate and excrete the dialysate via the urinary tract. In some variations, a method may include delivering a dialysate via the esophagus of a patient and draining the dialysate into a bladder of the patient. Delivering the dialysate may further comprise delivering the dialysate through the nasopharynx or oropharynx. Delivering the dialysate through the oropharynx may comprise the patient drinking the dialysate.

Provided is a circulation pipeline (10) for intracavity hyperthermic perfusion, the circulation pipeline comprising a heating tank (100), a liquid intake pipeline (101), a liquid discharge pipeline (102), a circulating pump (200), a pre-filling pipeline (103), a liquid return pipeline (104), a cavity entry pipeline (105) and a cavity exit pipeline (106), wherein a liquid storage cavity (100a) is formed in the heating tank (100), and the liquid intake pipeline (101) is in communication with the liquid storage cavity (100a). A medicinal liquid enters the liquid storage cavity (100a) of the heating tank (100) through the liquid intake pipeline (101).

A urinary catheter with deflectable tip, comprising a hollow catheter body configured to be inserted within the urethra of a patient, the catheter body having an elongate portion, a tip portion near a distal end of the elongate portion and an engagement portion spaced from the distal end where a user can grasp the catheter, the tip portion being deflectable for the purpose of steering the catheter within the urethra to allow the catheter to follow a natural curvature of the urethra, the tip portion being movable from a generally straight condition to a deflected condition wherein deflection of the tip portion occurs while the elongate portion remains generally straight.

Devices that are placed within fluid-filled organs, such as the bladder, which reduce the risk of bacterial infections using a combination of active agents and mechanical disruption of bacteria.

A percutaneous urinary catheter is provided, including a proximal portion, a distal portion configured to be deployed in a kidney and/or renal pelvis of the urinary tract, and at least one lumen extending at least partially through the proximal portion of the percutaneous urinary catheter; and a negative pressure source in fluid communication with the at least one lumen, the negative pressure source being configured to draw fluid from the urinary tract into the at least one lumen of the percutaneous urinary catheter for removal of the fluid from the urinary tract.

A urinary drainage system is disclosed herein. The urinary drainage system can include an air pressure apparatus with a connector having an elongate connector body. The connector includes a lumen having a larger proximal lumen diameter and a smaller distal lumen diameter. The system includes an air intake adapter having an elongate adapter body, including a proximal end having a proximal opening configured to be coupled to the distal end of the connector. The adapter can include an air intake port in fluid communication with the adapter lumen, the adapter lumen having a larger proximal lumen diameter and a smaller distal lumen diameter.

A catheter assembly having the major components: a cap, an introducer tip, four different variations of grip housing, a tube gripper and a catheter. The variations of the housing connected to the catheter assembly allows for safe and effective delivery of the anesthetics to various bodily orifices. The catheter is slowly advanced further while irrigating and dispensing the medication and/or lidocaine gel from the syringe. Once the desired depth is reached the practitioner can mark off the depth in centimeters on the catheter using a variation of the marker.

A direct sodium removal (“DSR”) infusate regimen and methods of use are provided for removing sodium and reducing fluid overload in patients with severe renal dysfunction and/or heart failure, in which a patient has at least a first DSR session with a first DSR infusate having no or low sodium that is instilled into a patient's peritoneal cavity for a first dwell period to cause sodium and excess fluid to migrate to the patient's peritoneal cavity, and thereafter, the patient may undergo conventional dialysis to rebalance the patient's fluid and sodium levels.