A system and method for draining excessive fluid from a body cavity or space. The system comprises an implantable fluid penetrable chamber comprising a frame covered by a fluid permeable mesh configured to enable fluids to penetrate therethrough. The system further comprises a catheter connected at a first end to one of said chamber sides/walls or penetrates therethrough; and optionally further comprises a pump placed inside or outside of said chamber.

A cannula comprising a hollow tube made of a biocompatible, thermoplastic polymer, memory shape material, tipped with an injection needle at it distal end, assumes desired shapes as it distally emerges from a lumen or channel of an instrument such as an introducer or endoscope. The desires shape includes a curvature conforming to an inverse tangent function. The cannula may be supplied alone, with or without an injection needle, and in a sterile pouch, for use with a device of an user's choice that has a suitable lumen or channel to guide the cannula, of the cannula may be used without such an instrument.

A fluid collection catheter includes an elongated tube having a proximal portion, a distal portion having a distal end, and a sidewall extending between a proximal end and the distal end thereof defining at least one drainage lumen. The sidewall of the tube includes a drainage portion. The fluid collection catheter also includes a tissue support having at least a first flange including a central portion connected to the distal portion of the tube and an outer portion extending radially and axially therefrom. The first flange can be configured to be deployed in a patient's bladder to maintain the distal end of the tube at a position in the bladder. When deployed, the tissue support defines a three-dimensional shape of sufficient size to permit flow of fluid contained in the bladder from the bladder through the drainage portion of the tube to the at least one drainage lumen.

Ureteral or bladder catheters are provided, including (a) a proximal portion; and (b) a distal portion, the distal portion including a retention portion that includes one or more protected drainage holes, ports or perforations and is configured to establish an outer periphery or protective surface area that inhibits mucosal tissue from occluding the one or more protected drainage holes, ports or perforations upon application of negative pressure through the catheter. Systems, kits and methods for inducing negative pressure to increase renal function also are provided.

A medical device for providing direct port-like endoscopic access to the urinary bladder, or other orifice, of a patient and a method of utilizing and inserting the medical device. The medical device can include a hollow tube with a main channel and a separate channel, a cap with an inflation port and a hollow flexible stem fluidly connecting the inflation port and the separate channel. A method can include inserting a needle above the pubic symphysis of a mammal, threading a guide wire through the needle, removing the needle and inserting the medical device. The method can optionally include determining measuring the depth between the skin surface of the patient's suprapubic region and urinary bladder.

A catheter for measuring pressure in the urinary tract of a patient includes a catheter body having a proximal and distal end. A plurality of lumens is formed in the catheter body, and an adaptor is coupled to the proximal end of the catheter body. The adaptor includes a port for each lumen. A first pressure sensor, typically including a balloon, is fluidically coupled to a first lumen and is configured and positioned to measure pressure in a urethra of the patient. A second pressure sensor, also typically including a balloon, is fluidically coupled to a second lumen and is configured and positioned on the catheter body to measure pressure in a bladder of the patient. An expandable retention member, which may be coupled to a third lumen, is positioned on the catheter body between the first and second expandable pressure sensors so that the catheter body may be retained at a selected location in the urinary tract to properly position the fluid pressure sensors in the bladder and urethra, respectively.

Methods, devices, and medicaments that include oxaliplatin are provided for use in the treatment of bladder cancer by locally administering oxaliplatin into the bladder of a patient to achieve a sustained concentration of oxaliplatin in urine in the bladder sufficient to produce a therapeutic concentration of oxaliplatin in bladder tissue. The oxaliplatin may be delivered into the bladder from an intravesical drug delivery device inserted into the bladder, wherein the device continuously releases the oxaliplatin into the urine in the bladder over an extended period of hours or days.

A sterile dual-purpose closed intermittent urinary catheter system that may be used as either a drain line or a collection bag. A catheter resides within an inner cavity of an extensible sheath and may be extracted from a forward end through a hub for insertion into the urethra. A valve at a rearward end of the sheath may be opened to permit the sheath to function as a drain line, or closed to permit the sheath to function as a collection bag. The sheath has an extended length substantially longer than the catheter length. The catheter is extracted from within the sheath and inserted into the urethra to start urine flow. The urine may be collected in the sheath with the valve closed, or drained straight into a toilet with the valve open. The hub may have a source of lubrication to wet the catheter as it passes through.

An intermittent urinary catheter assembly (20) comprises a catheter tube (22) having a proximal insertion end (24) and a distal end (26) remote from the proximal insertion end and a lumen (28) which extends from at or near the proximal insertion end to the distal end for draining urine from a human bladder. The intermittent urinary catheter assembly includes a urine discharge sleeve (34) associated with the discharge opening (30) of the catheter tube, and the urine discharge sleeve has a compact stowed configuration and is extendable into a deployed configuration for directing urine flow. Alternatively, an adapter assembly (50) comprises a fitting or nipple (52) having a urine passageway for insertion into a funnel (40) associated with a urine discharge end of an intermittent urinary catheter, and a discharge funnel (42) associated with the fitting or nipple, and an extendable urine discharge sleeve (34) within the discharge funnel.

An indwelling urinary catheter system having an elongated tubular catheter body 401 having a distal end and a proximal end; at least one sleeve portion 406 constructed out of a semi-permeable membranes surrounding at least one portion of the catheter body; at least one lumen to instill fluid into the catheter body; and a means to continuously efflux the instilled fluid through the semi-permeable membrane for circumferential egress of fluid out of the membrane around the catheter body. The catheter may further include a drainage lumen 414 extending through the catheter body from just short of the distal end to the proximal end and an opening or eyelet 405 in the catheter body just short of the distal end of the catheter body to permit urine to drain from a patient's bladder into the drainage lumen. A retaining mechanism may also be comprised.