An apparatus for sensing a property of a bladder wall, such as bladder-wall oxygen, comprises an elongate catheter (1) and an elongate sensor (2). The catheter (1) defines a path from a proximal end of the catheter to a distal end of the catheter. The catheter comprises a sensor channel for guiding the elongate sensor along at least a part of the path, the sensor channel opening at a sensor port (3) towards the proximal end of the catheter. The sensor channel comprises (i) an enclosed lumen portion (10), arranged to surround the sensor, and (ii) an open furrow portion (16). The furrow is located nearer to the distal end of the catheter than is the enclosed lumen. The furrow is arranged to allow the sensor (2) to exit the enclosed lumen (10) in a direction substantially parallel to, or tangential to, the path of the catheter (1) at a proximal end of the furrow.

Methods, devices, and medicaments that include a drug are provided for use in the treatment of the prostate by locally administering the drug into the bladder of a patient to achieve a sustained concentration of the drug in urine in the bladder sufficient to produce a therapeutic concentration of the drug in the prostate. The drug may be delivered into the bladder from an intravesical drug delivery device inserted into the bladder, wherein the device continuously releases the drug into the urine in the bladder over an extended period of hours or days.

The present invention relates to systems and methods for controlling flow through the urinary bladder and, more specifically, systems and methods for controlling continuous bladder irrigation after surgical treatment of lower urinary tract disorders. The control system for continuous bladder irrigation includes a catheter having a first port though which a first fluid enters a bladder and a second port through a second fluid exits the bladder; a first flow speed sensor for measuring a first speed of the first fluid; a second flow speed sensor for measuring a second speed of the second fluid; a control unit for sending, based on the first and second speeds, a warning signal of an abnormality in infusing the first fluid into the bladder and in draining the second fluid from the bladder.

Systems, devices and methods for draining and analyzing bodily fluids are disclosed in which a drainage assembly is configured to prevent negative pressure build-up. The drainage assembly generally includes a catheter which may include a drainage lumen, a reservoir, a venting mechanism in fluid communication with the drainage lumen and a positive pressure lumen, and a controller. The venting mechanism may further include a valve which is configured to maintain a closed position, as well as a vent in fluid communication with the valve, where the venting mechanism is configured to inhibit wetting of the vent from fluid within the drainage lumen.

Compositions and methods for the application of non-toxic bioparticle (e.g., extracellular vesicle (EV)) absorbing materials (e.g., non-toxic exosome reducing materials) for prophylactic, therapeutic, validation and/or experimental purposes are provided.

An implant delivery system can be configured to deliver an inflatable implant into a bladder via a urethra. The delivery system can comprise an elongate tubular body, an inflation tube and an implant decoupler. The tubular body can comprise a central lumen configured to hold an inflatable implant in an initial un-inflated state for delivery of the implant into the bladder. A method of use can include passing a distal tip of the elongate tubular body into the bladder. The implant can be inflated and released into the bladder.

Devices and methods are provided to facilitate self-catheterization of a urethra. In an exemplary embodiment, the device includes an elongate anchor member comprising a proximal end and a rounded distal end to facilitate insertion into a user's vagina, a bridge extending laterally from an intermediate location of the anchor member, a guide on the bridge spaced apart from the anchor member such that the guide is aligned with the user's urethra, the guide including a passage therethrough sized to receive a urinary catheter therethrough, and a handle on the proximal end of the anchor member to facilitate manipulation by the user and consistent, accurate alignment of the guide.

A urinary drainage system is disclosed herein. The urinary drainage system can include an air pressure apparatus with a connector having an elongate connector body. The connector includes a lumen having a larger proximal lumen diameter and a smaller distal lumen diameter. The system includes an air intake adapter having an elongate adapter body, including a proximal end having a proximal opening configured to be coupled to the distal end of the connector. The adapter can include an air intake port in fluid communication with the adapter lumen, the adapter lumen having a larger proximal lumen diameter and a smaller distal lumen diameter.

Various embodiments disclosed relate to drug-coated balloon catheters for treating, preventing, or reducing the recurrence of a stricture and/or cancer, or for treating benign prostatic hyperplasia (BPH), in a non-vascular body lumen and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent. In some embodiments, the balloon catheter includes a length-control mechanism which stretches and elongates the balloon when it is in a deflated state, giving the balloon a smaller cross-sectional deflated profile for tracking through the body lumen and for removal after treatment.

Ureteral catheters and assemblies are provided including: a drainage lumen including a proximal portion configured to be positioned in at least a portion of a patient's urethra and a distal portion configured to be positioned in a patient's ureter and/or kidney, the distal portion including a coiled retention portion including at least a first coil having a first diameter and a second coil having a second diameter, the first diameter being less than the second diameter; or wherein the retention portion extends radially outwardly from a portion of the distal end of the drainage lumen portion, the retention portion including a proximal end having a first diameter, a distal end having a second diameter, and a wall and/or surface extending therebetween, the retention portion having a second diameter is greater than the first diameter when deployed; or wherein the retention portion includes a plurality of drainage tubes.