The present invention is a self-cleaning catheter designed to impede the development of biofilm within the catheter and provide a mechanism for removing biofilm within the catheter during use by a patient. The self-cleaning catheter includes an outer shell enclosing a urine lumen. The urine lumen has the ability to be opened and closed with a urine lumen closure device and is formed with a plurality of micro ports and a plurality of macro wash ports. At least one antimicrobial lumen is affixed to the exterior of and in fluid communication with the urine lumen at the plurality of micro ports. Similarly, at least one wash lumen is affixed to the exterior of and in fluid communication with the urine lumen at the plurality of macro wash ports. Antimicrobial solutions and wash solutions are introduced into the urine lumen by the antimicrobial lumen and wash lumen respectively, even during use.

Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent.

Disclosed herein are systems, devices, and methods for the removal of objects from the body. The device may be a urethral catheter configured to aspirate kidney stones from the urinary tract through one or more aspiration ports at the distal face or along a lateral side of the catheter. The catheter may include one or more irrigation ports at the distal face or along the lateral side of the catheter for dislodging kidney stones. The device may be steerable. The spatial arrangement of the one or more irrigation ports with respect to the one or more aspiration ports may vary. The device may include an irrigation tube and/or a shield member configured to spatially confine the kidney stones adjacent the catheter. Various temporal patterns of aspiration and irrigation are disclosed for optimizing removal of kidney stones.

A method of stabilizing a tube at a stoma of a patient includes providing a stabilizing device having a base portion and a tube holding portion that is attached at the base portion via at least two legs and that, with the base portion affixed to the patient, is spaced from the stoma of the patient. The tube holding portion has a passageway therethrough that is configured to receive the tube that passes through the stoma. The tube holding portion may be adjusted to position the tube in a free-flow orientation or a restricted-flow orientation. The tube holding portion may include a disinfecting wiping element. The stabilizing device may have pads coupled to respective legs via an elastomeric connecting element to allow for adjustment of the pads relative to the legs. The tube holding portion may include flexible tabs that deflect to enlarge an effective diameter of the passageway.

A method is provided for facilitating urine output from the kidney, including: (a) inserting a catheter including: a drainage lumen including a distal portion configured to be positioned in a patient's kidney, renal pelvis and/or in the ureter adjacent to the renal pelvis and a proximal portion, the distal portion including a retention portion including a funnel support including at least one sidewall, wherein the funnel support includes a first diameter and a second diameter, the first diameter being less than the second diameter, the second diameter being closer to an end of the distal portion of the drainage lumen than the first diameter, wherein the proximal portion of the drainage lumen is essentially free of or free of openings; and (b) applying negative pressure to the proximal portion of the drainage lumen for a period of time to facilitate urine output from the kidney.

A ureteral catheter includes a drainage lumen having a proximal portion configured to be positioned in at least a portion of a patient's urethra and/or bladder and a distal portion configured to be positioned in a patient's kidney, renal pelvis, and/or in the ureter adjacent to the renal pelvis. The distal portion includes a retention portion for maintaining positioning of the distal portion of the drainage lumen. The retention portion includes a plurality of sections, each section having one or more openings on a sidewall of the retention portion for permitting fluid flow into the drainage lumen. A total area of openings of a first section of the plurality of sections is less than a total area of openings of an adjacent second section of the plurality of sections. The second section is closer to a distal end of the drainage lumen than the first section.

A method for administering chemotherapy medicament, which comprises providing a closed-system drug administration kit, performing sterile catheterization on a patient by placing at least the distal tip of the catheter into the patient's bladder to drain the bladder, inserting a syringe containing the medicament into a safety adapter at a proximal end of the catheter to prevent leakage during attachment, injecting the medicament into the bladder with the injector through the adapter and the drain lumen without leakage of the medicament from the patient into an environment while assessing a pain level of the patient, removing the syringe and closing the catheter to hold the medicament in the bladder for a given treatment time, and, after the given treatment time, draining the medicament out of the bladder with a medicament pressure reservoir through the catheter and into the medicament pressure reservoir for disposal of the kit.

A urinary catheter cap includes a main body that includes a urine introduction passage including a connection hole configured to be connected to a urinary catheter and a drain hole for draining urine, a lid portion that has a tubularly formed portion having a first end portion at the drain hole side and a second end portion at an opposite side and opens and closes the drain hole, a partition portion that divides the tubular portion of the lid portion into a plurality of spaces, and a hydrophobic film that is formed such that the hydrophobic film blocks at least two or more of the spaces at the second end portion of the lid portion. The partition portion may include a partitioning plate that is installed between a plurality of locations of an inner circumferential portion of the tubular portion of the lid portion.

A sustained drain system circuit and a sustained drain quality control system are constructed in which no mechanical or electrical driving and control mechanism is required at all, siphoning automatically occurs when some volume of urine is retained in the urinary bladder by the mass of urine, its potential energy, intrinsic pressure of filling and contraction of the urinary bladder, and abdominal pressure, and sustained drain continues even with a portion with a height difference higher than a drain source. In the sustained drain system circuit, a fluid is caused to be sustainedly drained by siphoning from an intracorporeal elastic closed space that can extend and contract as a drain source. The circuit is a siphoning circuit in which an inner diameter of a pipe space is designed so that a siphoning volume condition is satisfied and the fluid is drained as filling without a gap.

Lumen-apposing shunt devices for transporting body fluid from a first compartment (e.g., peritoneal cavity) to a second compartment (e.g., bladder) comprise a longitudinal tube communicating between the two compartments and retention systems that separate apart and maintain each end of the tube within the respective compartment. The retention systems include double self-expandable wheels and double inflatable balloons enveloping the tube transversely, with one wheel or balloon in the first compartment and the other wheel or balloon in the second compartment. The self-expanded wheels or inflated balloons support and retain the shunt device between the compartments as fluid (e.g., ascites) from the first compartment flows into the second compartment in response to pressure gradients between the compartments. The shunt device contains a one-way valve mechanism to provide unidirectional flow of fluid from the first to the second compartment and to prevent reflux from the second to the first compartment.