Described are systems and methods for compensating long term sensitivity drift of catalytic type electrochemical gas sensors used in systems for delivering therapeutic nitric oxide (NO) gas to a patient by compensating for drift that may be specific to the sensors atypical use in systems for delivering therapeutic nitric oxide gas to a patient. In at least some instances, the long term sensitivity drift of catalytic type electrochemical gas sensors can be addressed using calibration schedules, which can factor in the absolute change in set dose of NO being delivered to the patient that can drive one or more baseline calibrations. The calibration schedules can be used reduce the amount of times the sensor goes offline. Systems and methods described may factor in in actions occurring at the delivery system and/or aspects of the surrounding environment, prior to performing a baseline calibration, and may postpone the calibration and/or rejected using the sensor's output for the calibration.

A cartridge-based computer controlled self-injection device automatically regulates time and dosage administered to a patient. Cartridges can be electronically tagged so the injection device can determine the content, volume, expiration date, and physician prescribed dosage timetable. Authentication verifies the device and ensures the proper patient is using the device with the appropriate therapeutic injectant. Authentication further provides information controlling device operation including expiration dates and clock synchronization. Therapeutic injectant administration statistics, such as date and time of administration of a therapeutic injectant are stored and provide to a health care provider for monitoring. Patients can be notified of nearing or missed administrations.

A fluid dispenser device comprising: a reservoir (10) containing one or more doses of fluid; a resilient element (20), such as a spring, for urging said reservoir (10) to move axially between a rest position and at least one actuated position; and blocking means (30; 51, 53, 55) for preventing said reservoir (10) from moving axially; said blocking means being movable manually in a direction that is different from the direction of said axial movement of the reservoir (10) so as to allow said reservoir (10) to move axially; said blocking means comprising a plate (30) provided with an opening (31) comprising a first opening portion (31a) of smaller size, and a second opening portion (31b) of larger size, said first and second opening portions (31a, 31b) being interconnected, said plate (30) being movable radially between a blocking position in which said first opening portion (31a) co-operates with said reservoir (10) so as to block it axially, and a non-blocking position in which said second opening portion (31b) co-operates with said reservoir (10) so as to allow said reservoir (10) to move axially under the effect of said resilient element (20).

A control body and cartridge that are coupleable with one another to form an aerosol delivery device are provided. The control body comprises a control component and an RFID reader contained within at least one housing. The cartridge comprises at least one heating element and an RFID tag contained within at least one housing. The RFID reader of the control body is coupled to the control component of the control body and configured to communicate with the RFID tag of the cartridge upon coupling of the control body with the cartridge. The control component of the control body is configured to authorize the cartridge for use with the control body based at least in part on communication between the RFID reader and the RFID tag.

A patient care system is configured for infusing fluid to a patient. The system includes a plurality of modular fluid infusion pumps that each has a connector for connecting to a modular programming unit or to one another. Systems and methods are configured for verifying that the connectors are reliably performing their functions or communicatively connecting the pumps to one another or to the programming unit.

A droplet delivery device and related methods for delivering precise and repeatable dosages to a subject for pulmonary use is disclosed. The droplet delivery device includes a housing, a reservoir, and ejector mechanism, and at least one differential pressure sensor. The droplet delivery device is automatically breath actuated by the user when the differential pressure sensor senses a predetermined pressure change within housing. The droplet delivery device is then actuated to generate a stream of droplets having an average ejected droplet diameter within the respirable size range, e.g, less than about 5 μm, so as to target the pulmonary system of the user.

Systems and methods for automatically delivering medication to a user. An automated drug delivery system may include a sensor and a wearable automated drug delivery device. The wearable automated drug delivery device may be configured to couple to the skin of a user and may include a controller and a pump. The pump may be configured to output the medication. The controller may be within the wearable automated drug delivery device. The sensor may be coupled to the user and may be configured to collect information regarding the user. The controller of the wearable automated drug delivery device may use the collected information to locally determine an amount of medication to be output from the wearable automated drug delivery device and cause delivery of the amount of medication.

A collapsible inhaler for use with a metered dose inhaler (MDI) dispenser that is operable to dispense a metered dose of medicament therefrom, the inhaler including: an inlet member being adapted to receive an MDI dispenser and having an inlet therein; an outlet member having an outlet therein, a conduit which is pliable and has a distal end associated with the inlet member and a proximal end associated with the outlet member, a support associated with the pliable conduit that is adjustable between an expanded state and a contracted state whereby in the contracted state the inlet member is positioned proximate the outlet member, while in the expanded state the support supports the pliable conduit and combined with the inlet member being spaced from the outlet member that defines a chamber, so that in use a metered dose of medicament can be dispensed from the MDI dispenser through the inlet in the inlet member to mix with air in the chamber and be inhaled by a patient through the outlet in the outlet member, wherein the inhaler further includes a lockout mechanism for inhibiting operation of the MDI dispenser when the support and conduit are in the contracted state and not inhibiting operation of the MDI dispenser when the support and conduit are in the expanded state.

In some embodiments, a system includes a cartridge assembly and a pen assembly. The cartridge assembly includes a mouthpiece assembly and a bracket cartridge assembly. The mouthpiece assembly includes a mouthpiece component defining a mouthpiece opening and an outer housing defining a vapor outlet and including a recessed sidewall portion. The pen assembly includes a pen housing and a bracket assembly configured to engage with the bracket cartridge assembly of the cartridge assembly such that a temperature of a coil of a wick assembly of the cartridge assembly may be increased such that a carrier material disposed near the coil may be vaporized by the coil. When the cartridge assembly is engaged with the pen housing, the recessed sidewall portion of the outer housing and an inner surface of the pen housing form a fluid path from the vapor outlet to the mouthpiece opening.

A nasal prong or nasal mask cannula system which has at least one of the following features: to enhance the cannula tubing at the port base of the oxygen source to minimize “crimping” and diminished oxygen delivery; to design a cannula that will expand in length as needed and shorten as needed without loss of pressure (PSI) of oxygen from start point of oxygen source to patient; to provide a device such as a clasp or clip attached to the cannula which clasp or clip may be attached to the patient's clothing to relieve pressure or weight exerted by the cannula tubing on the patient's ears and keep the cannula close to the patient's body; to provide storage means for storing extra length of tubing; to provide a warning device to alert the patient when oxygen levels or oxygen flow rate are low or that the battery energizing the warning device is low; to provide a timing device to alert the patient to change the cannula after a prescribed period of time; to provide means for stylizing or personalizing the cannula system; to provide an oxygen supply system with a regulator which includes an external outlet or port that includes a pivot of at least 180° and optimally 360°.