In a corneal measurement system, an optical element focuses an excitation light to an area of corneal tissue at a selected depth. In response, a fluorescing agent applied to the cornea generates a fluorescence emission. An aperture of a pinhole structure selectively transmits the fluorescence emission from the area of corneal tissue at the selected depth. A detector captures the selected fluorescence emission transmitted by the aperture and communicates information relating to a measurement of the selected fluorescence emission captured by the detector. A controller receives the information from the detector and determines a measurement of the fluorescing agent in the area of corneal tissue at the selected depth. The system may include a scan mechanism that causes the optical element to scan the cornea at a plurality of depths, and the controller may determine a measurement of the fluorescing agent in the cornea as a function of depth.

An instrument to facilitate hands-free illumination of an eye for a surgical procedure. The instrument includes an optical end of unique architecture and surfacing such that the instrument may be left immobile while sufficiently illuminating an eye interior with greater than 100° of wide beam spread angle provided. Further, the grind surfacing provided to the end cone of the optical end provides enhanced light distribution.

The present disclosure relates generally to illumination devices, systems, and methods for ophthalmic surgical procedures. Certain aspects of the present disclosure provide an illumination system which monitors and determines the amount of light delivered to a tissue within the ocular space, based upon data received from an imaging system. In certain aspects, if the amount of light delivered to the tissue is determined to be excessive, the illumination system may modify at least one parameter associated with the delivered light to reduce and/or eliminate phototoxic effects thereof. In certain aspects, if the amount of light delivered to the tissue is determined to be excessive, the illumination system may alert a surgeon, who may then trigger modification of the at least one parameter associated with the delivered light to reduce and/or eliminate phototoxic effects thereof.

A device and a method for irradiating the cornea of an eye, wherein the device includes at least the following elements: a ring body, which has a bearing surface embodied concentrically about the longitudinal axis of the device for the purpose of fastening the device on the eye, an irradiation channel for irradiating the cornea, which is located inside the ring body, a light source, which, in the operationally-ready state of the device, is attached inside the ring body for emitting light in the irradiation channel, wherein the bearing surface for fastening the device is arranged outside the irradiation channel, which has the result that the irradiated area itself is not additionally loaded by bearing surfaces of the device.

An ophthalmic treatment system and method for performing therapy on target tissue in a patient's eye. A delivery system delivers treatment light to the patient's eye and a camera captures a live image of the patient's eye. Control electronics control the delivery system, register a pre-treatment image of the patient's eye to the camera's live image (where the pre-treatment image includes a treatment template that identifies target tissue within the patient's eye), and verify whether or not the delivery system is aligned to the target tissue defined by the treatment template. The control electronics control the delivery system to project the treatment light onto the patient's eye in response to both an activation of a trigger device and the verification that the delivery system is aligned to the target tissue, as well as adjust delivery system alignment to track eye movement.

The detailed characteristics of the red fluorescence of the human lens—that occurs at the seventh decade of life—is recognized as an example of evolutionary photobiomodulation for repair of the retina, and then used as a paradigm for extending current parametric values for reproducible photobiomodulation. The new photobiomodulation parameters involve relative intensities for wavelength bands within the range of 600 nm to 900 nm.

The present disclosure is related to a treatment probe and method for treating dry eye. The treatment probe may include a thin stainless steel tip, a spacer to ensure proper contact and protect the skin of a patient, a sensor to provide temperature feedback to the power supply providing RF energy to the treatment probe. The treatment focuses on a patient's temple and periorbital area.

A dual blade device and method useable for performing an ab interno procedure within a human eye to remove a strip of trabecular meshwork tissue.

A method is provided for treating a targeted area of ocular tissue in a tissue-sparing manner comprising use of two or more therapeutic modalities, including thermal radiation source (such as an CW infrared fiber laser), operative in a wavelength range that has a high absorption in water, and photochemical collagen cross-linking (CXL), together with one or more specific system improvements, such as pen-operative feedback measurements for tailoring of the therapeutic modalities, an ocular tissue surface thermal control/cooling mechanism and a source of deuterated water/riboflavin solution in a delivery system targeting ocular tissue in the presence of the ultraviolet radiation. Additional methods of rapid cross-linking (RXL), are provided that enables cross-linking (CXL) therapy to be combined with thermal therapy.

A system for the treatment of the dry eye syndrome that is based on a light source. The system includes a disposable tip, to treat an eyelid. A corneal shield is used to protect the patient's eye.