Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent.

Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent.

A system for removing fluid from a urinary tract includes at least one sensor configured to detect signal(s) representative of pulmonary artery pressure and communicate signal(s) representative of the pulmonary artery pressure and a controller. The controller is configured to: receive and process the signal(s) from the at least one sensor to determine if the pulmonary artery pressure is above, below, or at a predetermined value; and provide a control signal, determined at least in part from the pulmonary artery pressure signal(s) received from the at least one sensor, to a negative pressure source to apply negative pressure to a urinary catheter to remove fluid from a urinary tract when the pulmonary artery pressure is above the predetermined value and to cease applying negative pressure when the pulmonary artery pressure is at or below the predetermined value.

A system for removing fluid from a urinary tract includes: at least one sensor configured to detect signal(s) representative of bioelectrical impedance and communicate signal(s) representative of the impedance; and a controller. The controller is configured to: receive and process the signal(s) from the at least one sensor to determine if the impedance is above, below, or at a predetermined value; and provide a control signal, determined at least in part from the signal(s) representative of the impedance received from the at least one sensor, to a negative pressure source to apply negative pressure to a urinary catheter when the impedance is below the predetermined value and to cease applying negative pressure when the impedance is at or above the predetermined value.

A urinary catheter is described that can be retained inside the body for extended periods. A catheter mating device can connect to the catheter to move the catheter inside of the body or remove it from the body. The catheter includes one or more of: (1) a retention portion having an outer cover, an inner cavity, and at least one structure in the inner cavity that exerts outward force on the outer cover, and (2) an extendable flap at the catheter's distal end. The retention portion and/or extendable flap each are configured to retain the catheter in the proper position inside of a user's body.

A direct sodium removal (“DSR”) infusate regimen and methods of use are provided for removing sodium and reducing fluid overload in patients with severe renal dysfunction and/or heart failure, in which a patient has at least a first DSR session with a first DSR infusate having no or low sodium that is instilled into a patient's peritoneal cavity for a first dwell period to cause sodium and excess fluid to migrate to the patient's peritoneal cavity, and thereafter, the patient may undergo conventional dialysis to rebalance the patient's fluid and sodium levels.

A device can be coupled to a foley catheter inserted into the bladder of a patient, where the foley catheter includes a urine passage through which urine can be drained from the bladder. The device includes a pressure sensor that is connected to a urine outlet of the urine passage and configured to measure a pressure value of the urine being drained through the urine outlet, a processor connected to the pressure sensor and configured to determine whether the foley catheter can be removed by comparing the pressure value and a predetermined threshold value, and a display unit connected to the processor and displaying whether the foley catheter can be removed according to the control of the processor.

An intermittent catheter, preferably a female intermittent catheter, is provided in an assembly. The assembly may include a cap which may be attachable to the base of the assembly in use, and/or a seal which misaligns with sealing surfaces of a chamber wall and a moveable insert in use. It may have a two-step deployment, and/or a sheath that pulls out a storage chamber. Internal and external housing may define the storage chamber. The housing may have a filling aperture and/or the storage chamber may comprise an insert configured to move axially in response to rotation.

An intermittent catheter, preferably a female intermittent catheter, is provided in an assembly. The assembly may include a cap which may be attachable to the base of the assembly in use, and/or a seal which misaligns with sealing surfaces of a chamber wall and a moveable insert in use. It may have a two-step deployment, and/or a sheath that pulls out a storage chamber. Internal and external housing may define the storage chamber. The housing may have a filling aperture and/or the storage chamber may comprise an insert configured to move axially in response to rotation.

Systems and methods are configured for combined fluorescence imaging and white light imaging of tissue such as during surgical endoscopic procedures. A chip-on-tip type endoscope can be equipped with both white light and blue light LEDs. A single camera or dual cameras are configured with backside illuminated CMOS image sensor(s) to receive and process the white light and fluorescence images. The light sources, image sensors and image processing circuitry are configured to synchronously emit light and record pixels for visible white light and fluorescence frames alternately. Global or quasi-global shuttering can be used on the image sensor(s). A modified color filter array and other filters can be provided to enhance fluorescence imaging capabilities. Insufflating gas clears debris from the camera field of view and aids in moving he cannula distally through a body passageway.