Implants comprising electrically-responsive hydrogel are described. Systems to provide electricity to induce response in hydrogel-containing implants are described. Methods for utilizing said system and methods for utilizing said hydrogel-containing implants are described.

In some examples, a catheter includes an elongated body defining an injection lumen, a drainage lumen, and an inflation lumen. The elongated body includes an anchoring member positioned on a proximal portion of the elongated body. A sensor is positioned on a distal portion of the elongated body or distal to a distal end of the elongated body. The medical device includes an active valve positioned in or about the drainage lumen The active valve is configured to move between a closed state in which, when a proximal end of the elongated body is positioned in a bladder of a patient, the active valve is configured to retain fluid in the bladder, and an open state in which the active valve enables drainage of fluid from the bladder via the drainage lumen.

The present invention relates to a catheter system for urine extraction comprising: (a) a genital adapter configured to fit a genitalia; (b) an adapter base connected to said genital adapter; (c) an operational tube connected to said adapter base; (d) a base unit, connected to said operational tube, and comprising an electric pump and a controller; (e) at least one control interface for commanding said controller; (f) a catheter tube having a first end for insertion into said base unit and having a second end for insertion into said operational tube, said adapter base, and said genital adapter; and (g) wherein said second end of said catheter tube is configured to extend through said genital adapter to the urinal bladder and to extract urine from said urinal bladder by said electric pump.

Disclosed is a method for treating a renal condition by loco-regional perfusion of one or both of a patient's kidneys (1810). A closed circuit may be formed with a perfusion catheter (1822) positioned in the renal artery of the kidney, a recovery catheter (1824) positioned in the renal vein of the kidney, and an external membrane oxygenator (1820) disposed therebetween. A perfusate containing, for example, a drug may be circulated through the closed circuit while isolating the closed circuit from the patient's systemic circulation.

An incremental syringe is provided and includes a syringe barrel, a finger grip disposed at the proximal end of the syringe barrel, a tab disposed inside the syringe barrel, and a plunger body having detentes, wherein the detentes are configured to interact with the tab to provide audible and tactile feedback to a user when the plunger body is pushed through the syringe barrel in a distal direction.

The present disclosure relates generally to the field of medical devices and establishing fluid communication between body lumens and/or within a body vessel. In particular, the present disclosure relates to devices and methods for establishing drainage between apposed body lumens and/or within a body vessel.

Disclosed is a Foley catheter which comprises a main tube, a positioning balloon portion, a urine drainage branch tube, an irrigation branch tube and a breaking portion. The main tube has a urine drainage lumen and an irrigation lumen. One end of the main tube has the positioning balloon portion communicated with the irrigation lumen, and the other end extends to form the urine drainage branch tube communicated with the urine drainage lumen and the irrigation branch tube communicated with the irrigation lumen. The breaking portion is formed at any one of positions including the position at the main tube, the urine drainage branch tube and the middle section of the irrigation branch tube, wherein the breaking portion is disposed in such a manner that the breaking portion will be broken when a tweak force exceeding a predetermined value is applied so that the Foley catheter is divided into two sections or the fluid in the positioning balloon portion flows out.

Impedance is detected between electrodes coupled to an indwelling medical device to monitor bacteria growth and/or formation of a bacterial biofilm in an in vivo environment. When an antimicrobial agent is present in the in vivo environment, the same voltage that enables impedance detection also generates a bioelectric effect, which decreases a size of the bacterial biofilm or inhibits growth of the bacterial biofilm. In some embodiments, the impedance detected between the electrodes can also be used as a feedback mechanism. When detection indicates that a bacterial biofilm has formed, the system can take remedial measures, such as introducing an antimicrobial agent to the in vivo environment and/or delivering a voltage higher than detecting voltage to deliver a greater bioelectric effect. In some embodiments, the electrodes can be formed on a flexible substrate that is mounted on and conforms to a non-flat surface of the indwelling medical device.

A packaged catheter equipped with a dispensing device and method of dispensing a packaged catheter using the dispensing device. The dispensing device is a pair of separately translatable movement control devices, each operably engaging the catheter for permitting unidirectional movement of the catheter in a first axial direction relative to the movement control devices.

Implantable drug delivery devices are provided to have a deployment shape for implantation in the body and a retention shape for retention in the body. The device may have one or more elongated drug reservoirs containing a drug, and the drug reservoir may be formed from a deformable material. In one case, a first filament is attached to the first end of the drug reservoir and second filament is attached to the second end of the drug reservoir, wherein a fastener is positioned about the first and second filaments to permit shortening and prevent lengthening of the filaments with reference to the ends of the drug reservoir, as a means for transforming the device from the implantation shape to the retention shape.