An external catheter stabilizer device for stabilizing and retaining a catheter tube at a stoma includes a base portion that is attached at a central portion via at least two legs. The base portion is configured to be affixed at a patient so as to generally surround a stoma. The central portion has a passageway therethrough that is configured to receive a tube that passes through the stoma. The central portion may include a disinfecting wiping element for receiving and wiping the tube as it is inserted through the passageway and into the stoma. The central portion may include flexible tabs that deflect to enlarge an effective diameter of the passageway and that are biased radially inward to retain the tube thereat. The device may have pads coupled to the respective legs via an elastomeric connecting element to allow for adjustment of the pads relative to the legs.

A method of treating a bladder condition is provided. The method is effected by circulating a volume of heated fluid through a urinary bladder of a subject in need and gradually increasing the volume of fluid up to a predetermined fluid volume and or pressure.

A catheter insertion device which employs back-and-forth longitudinal axial movement to advance the catheter by the cooperative interface of an incline ramp and a decline ramp with a split gripping mechanism is described.

Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent.

Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent.

The invention relates to a drug and device system for the directed application of a substance into a hollow space, such as a hollow organ, or into a body cavity of a patient, i.e. a mammalian patient, in particular for use in the course of a therapeutic pneumoperitoneum. In particular, herein the present invention is for use in cancer/tumor treatment, including metastatic forms thereof, and is also directed to a kit and its use in a method of treatment, comprising the said drug and device system for the said directed application. Especially, the invention pertains to a sterile and closed prefilled drug containing (medical) device system for administering at least one pharmaceutically active substance (drug) by pressurized aerosol therapy (PAT) in a hollow organ, or preferably in a body cavity, of a patient, in particular a therapeutic pneumoperitoneum, comprising a flexible package, comprising at least one container comprising at least one pharmaceutically active substance in powder, lyophilisate, solution, liquid, gel or other form (suspension, emulsion), and being provided with breakable, an openable, or perforable cap; and a bag of liquid diluent), wherein the bag is optionally equipped with at least one drain tube provided with a closing device; and wherein the bag is equipped with a mixing tube, optionally equipped with an openable closure, and which optionally ends with a perforation device, which container is preferably a vial, syringe, single-use syringe, ampoule, phial, or bottle, comprising the said pharmaceutically active substance, and which container is provided with breakable, an openable, or perforable cap; and wherein said package is comprising at least one flexible airtight sterile casing, containing said container, preferably a vial, syringe, single-use syringe, ampoule, phial, or bottle, of the said pharmaceutically active substance, and said perforation device, said container being housed in the casing; and wherein the said container is manually maneuverable from the outside of the casing in order to be opened inside the closed casing, optionally is manually maneuverable from the outside of the casing up to a perforating position of said cap through the same perforation device; and whereupon after opening of the said container and of the said closure, and selectively mixing (i.e. dissolving, reconstituting) the at least one pharmaceutically active substance (drug) with the liquid diluent through the mixing tube, a solution of the at least one pharmaceutically active substance (drug) in the liquid diluent is provided for administering by pressurized aerosol therapy (PAT) in a hollow organ, or preferably in a body cavity of a patient.

A multi-lumen catheter, for insertion into and draining a body cavity, that mitigates the risk of obstruction of the drainage ports and drainage lumen of the catheter, reduces the detrimental effects caused by the suction forces of the drainage ports on the body cavity being drained, and reduces the risk of infection of the body cavity being drained by decreasing the residual volume of fluid retained in the body cavity being drained. These advantages are achieved by the novel approach of disposing a perforated filter membrane or a membrane having a relatively large entry port(s) between membrane struts over a segmented retention element and also over the drainage port(s) of the drainage lumen of the catheter thereby creating internal interstitial drainage channels and internal interstitial drainage cavities.

A sterilized medical device assembly comprises a medical device having a hydrophilic surface on at least a part thereof, such as a hydrophilic urinary catheter, and a package forming a closed compartment accommodating the medical device. The medical device is arranged in an activated state in the package, with the hydrophilic surface being wetted with a wetting fluid. In addition, a small amount of wetting liquid is freely arranged in the closed compartment of the package, and in direct contact with the hydrophilic surface of the medical device. The volume of the wetting liquid corresponds to between 0.01% and 10% of a volume of the closed compartment. The medical device assembly is steam sterilized, and it has been found that the extra small amount of free liquid is very efficient in ensuring a reliable and efficient steam sterilization.

A compact catheter assembly (10) and methods of making such a catheter assembly are disclosed. The catheter assembly includes a receiver (14) and a catheter sub-assembly (16). The catheter sub-assembly includes a gripping member (18) and a catheter tube (20) carried by the gripping member.

One aspect of the invention provides an autonomous continuous bladder irrigation device including: a color sensor programmed to detect a color of outflow from a catheter; an occlusion unit programmed to adjustably occlude a lumen providing irrigation to the catheter; and a controller in communication with the color sensor and the occlusion unit and programmed to control the occlusion unit to titrate irrigation flow to the catheter based on the color detected by the color sensor in order achieve a specified color of outflow from the catheter.